The overarching goal of the Critical Assessment of Genome Interpretation (CAGI) is to establish the state of the art in the field of interpreting genomic variation through periodic editions of the CAGI experiment and extensive dissemination of their outcomes. For predictors, establishing state of the art involves recognizing best prediction strategies, highlighting innovation and identifying bottlenecks that prevent the field from advancing. For the user community, this involves providing trustworthy information about the most appropriate methods for a particular research or clinical application, and the best way to use the methods.
Why genome interpretation? Genomic variation is responsible for numerous rare diseases, for propensity for many common traits and diseases including cancer, for drug response, and is a key characteristic of cancer evolution. Genomic data therefore hold the promise of revolutionizing our understanding and treatment of human disease.
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CAGI7 Tracker ☀️
CAGI7 challenges
- Ongoing during summer and fall 2025. Twelve challenges announced, ten open for submission. ☀️
CAGI7 conference
- December 6-8, 2025 at Northeastern University in Boston. ☀️
CAGI7 special issue
- To be announced.
CAGI Educational Activities
Our past activities are listed on the CAGI MLD Bootcamp page.
Recent Announcements
September 9, 2025 ☀️
- CAGI7 Conference announced
June 2, 2025
- CAGI7 has started!
March 25, 2025
- CAGI6 special collection officially out. Twenty-two papers published.
Last updated: September 9, 2025