Two new CAGI 2012 challenges: lipid metabolism diseases FCH and HA

We have recently released two new CAGI 2012 challenges:

1. Using exome sequencing data from a family, identify which individual has hypoalphalipoproteinemia (HA) and other disease phenotypes.

2. In a family affected by familial combined hyperlipidemia (FCH), identify mutation(s) conferring low-density lipoprotein cholesterol (LDL-C) disease phenotype and identify individuals with abnormal triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C) levels.

Important! since this challenge was first posted, there have been important updates, namely
(a) a correction regarding who has the elevated LDL-C phenotype (Patient-17 is the unaffected daughter) and
(b) a clarification about how the variant calling was performed.