CAGI 2011

The second round of CAGI was completed in 2011, with 11 challenges provided to
predictors. The experiment yielded a total of 117 predictions from 21 groups from 18 countries, with 55 people attending the December 2011 meeting. Experimental results for the following CAGI 2011 challenges have been published:
Mouse exomes challenge: Fairfield et al., Mutation discovery in mice by whole exome sequencing. Genome Biology 2011, 12:R86. doi:10.1186/gb-2011-12-9-r86
Cancer cell lines challenge: Heiser LM et al., Subtype and pathway specific responses to anticancer compounds in breast cancer. doi: 10.1073/pnas.1018854108. CBS challenge: Mayfield JA, et al. Surrogate genetics and metabolic profiling for characterization of human disease alleles. Genetics. 2012, 190(4):1309-23. doi:10.1534/genetics.111.137471. CAGI was presented at ISMB/EECB 2011 in a special session in July, covered in GenomeWeb and in a special session at the Pacific Symposium on Biocomputing in January 2012.

The flagship manuscript describing the meeting as well as a collection of papers describing the predictions and challenges is currently underway.